Far Eastern squid liver may help suppress inflammation after kidney ischemia
Russian scientists have discovered that synaptamide, taken from the liver of Far Eastern squid, has the potential to suppress inflammation in the kidneys after ischemia. This substance reduces the production of pro-inflammatory molecules and decreases the influx of leukocytes into the kidneys.
Biologists hope that the research results will not only contribute to the development of effective therapy for kidney failure but also enhance understanding of the mechanisms of synaptamide action. This unique component could become key in combating ischemia of internal organs. It is expected that combining synaptamide with other protective drugs could lead to the development of innovative therapy to combat inflammation and kidney cell damage, as well as kidney failure.
Synaptamide, a derivative of unsaturated fatty acids found in Far Eastern squid, prevents inflammation after ischemia by interacting with the GPR110 receptor on the surface of immune cells, and this receptor plays a significant role in the development of inflammatory processes.
Photo: Fotodom