A novel method for bone tissue restoration has been developed, featuring a specialized tissue engineering structure where living cells are introduced.
Experts from the Y. L. Tsivyan Research Institute of Traumatology and Orthopedics in Novosibirsk presented a new method for bone tissue restoration, successfully tested on animals. This technique aims to stimulate bone regeneration, particularly for bones damaged due to injuries, diseases, or surgical interventions, offering patients with bone defects an effective means for bone recovery, contributing to the overall restoration of limb functions.
The tissue engineering structure comprises a structural biodegradable matrix, living cells, and growth factors extracted from the patient’s own body. Irina Kirillova, the head of the project and deputy director for research at the Y. L. Tsivyan Research Institute of Traumatology and Orthopedics, explained that the rigid matrix retains its shape and serves as a carrier for living cells. The presence of such a matrix creates suitable conditions for the colonization of living cells, ensuring their viability and promoting subsequent cell division.
The results of the study were verified on New Zealand White rabbits. The replacement of the bone defect led not only to the restoration of bone volume but also to an increase in its density.
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