Scientists recommend consuming pomegranates to help protect against Alzheimer’s disease, according to research published in the journal Alzheimer’s & Dementia. The study highlights the benefits of urolithin A, a compound found in pomegranates, strawberries, and walnuts, which can improve memory and assist individuals suffering from Alzheimer’s disease.
Mitophagy and Brain Health
Many neurodegenerative diseases, such as Alzheimer’s, are associated with mitochondrial dysfunction, known as mitophagy. This condition hinders the brain’s ability to clear out damaged mitochondria, which are crucial for cellular energy production. Accumulation of these defective mitochondria leads to deteriorating brain function.
Role of Nicotinamide Riboside (NAD)
Nicotinamide riboside (NAD) is a dietary supplement that aids in removing damaged mitochondria from the brain, proving beneficial for conditions like Parkinson’s and Alzheimer’s diseases. The researchers found that urolithin A has similar efficacy, improving memory and other symptoms in rodents involved in the study.
Pomegranate as a Source of Urolithin A
Pomegranates are a rich source of urolithin A. However, the precise dosage required to achieve a sustainable protective effect is not yet determined. Scientists believe that consuming more than one pomegranate per day may be necessary, but further human trials are needed to establish the exact dosage.
Availability and Safety of Urolithin A
Urolithin A is also available as a dietary supplement. However, additional research is required to confirm its safety and efficacy for human consumption.
Conclusion
While pomegranates and other sources of urolithin A show promise in protecting against Alzheimer’s disease by improving mitochondrial function and memory, further studies are needed to determine the appropriate dosage and ensure the safety of urolithin A supplements for humans.
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