Researchers from the National Research Center “Kurchatov Institute” have introduced a novel method for treating oncological diseases that focuses on targeting micrometastases using radionuclides. This innovative approach aims to reduce the negative impact of radiopharmaceuticals on the body.
Micrometastases are clusters of cancer cells measuring less than 1-2 mm, which cannot be detected through conventional diagnostic methods. After tumor removal surgery, patients are often recommended to undergo courses of chemotherapy or radionuclide therapy using alpha or beta emitters. The scientists have now proposed a new approach that minimizes the impact on the body by concentrating on localized effects on cancer cells.
The experts suggest using auger electron emitters, known as “short-range” radionuclides. The research revealed that these particles can damage cells within a radius of several dozen nanometers, minimizing cytotoxic effects over significant distances and without causing harm to healthy cells and tissues.
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