For the first time in Russia, scientists from Novosibirsk have identified genetic markers responsible for the development of uterine fibroids, a condition for which there is currently no medicinal treatment. These genetic markers provide an opportunity for early disease diagnosis and may serve as the basis for the future development of effective targeted therapies. The research conducted at the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences revealed approximately 20 genetic variants that are more common in patients with uterine fibroids compared to the control group.
These genes, responsible for protein synthesis, influence the growth and development of tumor cells. Detecting the combination of these genes in a healthy woman may indicate a high risk of developing uterine fibroids, allowing for recommendations on monitoring and planning reproductive functions.
The study, lasting more than six years and involving over 100 women, represents the first experience of its kind in Russia. The scientific researchers analyzed the DNA structure and the concentration of gene-encoded regulatory factors, followed by the use of bioinformatic analysis.
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