Scientists from the Omsk State Medical University have found that arrhythmia in young people can be caused by disruptions in myocardial structure, which are caused by connective tissue dysplasia. The research findings have been published in several scientific journals, including the Russian Cardiology Journal.
Connective tissue dysplasia (CTD) occurs due to genetically determined metabolic disorders during the development of the body’s connective tissue. Symptoms of CTD often manifest in childhood and actively develop during adolescence, in some cases continuing until the age of 45.
Individuals suffering from CTD experience difficulties during physical and emotional stress and often complain of cardiovascular and respiratory conditions. Additionally, they may have gastrointestinal problems.
It is challenging for doctors to assess the health of such patients, especially during military conscription, physical exertion, and pregnancy determination.
While isolated signs of connective tissue dysplasia may have no impact on health, involvement of multiple organs and systems poses a serious problem. In such cases, undifferentiated connective tissue dysplasia (UCTD) is diagnosed.
Scientists have determined that one in five individuals suffers from UCTD. They speculate that the high prevalence of this condition among Russians leads to an underestimation of the health potential of young working-age people. Cardiovascular pathology caused by UCTD can lead to premature death.
Researchers analyzed electrocardiogram monitoring data in young patients with UCTD and identified features of arrhythmic syndrome. They observed localized decrease in myocardial contractility, indicating morphological changes that lead to disturbances in heart rhythm, electrical conduction, and the development of arrhythmias.
According to scientists, it is necessary to develop treatment and rehabilitation methods for patients with UCTD, taking into account the characteristics of their clinical condition. Equally important is the development of methods for predicting the course of the disease, considering the risk of premature death.
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